Cu-Catalyzed Electrophilic Disulfur Transfer: Synthesis of Unsymmetrical Disulfides
Weiguo Wang, Yunzhi Lin, Yudao Ma, Chen-Ho Tung and Zhenghu Xu*
*Key Lab for Colloid and Interface Chemistry of Education Ministry, School of Chemistry and Chemical Engineering, Shandong University, Jinan 250100, P. R. China, Email: xuzhsdu.edu.cn
W. Wang, Y. Lin, Y. Ma, C.-H. Tung, Z. Xu, Org. Lett., 2018, 20, 3829-3832.
DOI: 10.1021/acs.orglett.8b01418 (free Supporting Information)
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In an efficient, copper-catalyzed electrophilic persulfuration reaction leading to unsymmetrical disulfides and polysulfides, various nucleophiles, including aryl boronic acids, β-keto esters, and thiols, can be used as substrates. This method offers simple and practical conditions, and general scope.
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