Double Dehydrogenation of Primary Amines to Nitriles by a Ruthenium Complex Featuring Pyrazole Functionality

Indranil Dutta, Sudhir Yadav, Abir Sarbajna, Subhabrata De, Markus Hölscher*, Walter Leitner and Jitendra K. Bera*

*RWTH Aachen University, Worringerweg 2, 52074 Aachen, Germany; Department of Chemistry, Indian Institute of Technology Kanpur, Kanpur 208016, India, Email: hoelscheritmc.rwth-aachen.de, jberaiitk.ac.in

I. Dutta, S. Yadav, A. Sarbajna, S. De, M. Hölscher, W. Leitner, J. K. Bera, J. Am. Chem. Soc., 2018, 140, 8662-8666.

DOI: 10.1021/jacs.8b05009

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Abstract

A ruthenium(II) complex bearing a naphthyridine-functionalized pyrazole ligand catalyzes an oxidant-free and acceptorless selective double dehydrogenation of primary amines to provide nitriles at moderate temperature.

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Key Words

nitriles

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ID: J48-Y2018