Merging Visible-Light Photocatalysis and Transition-Metal Catalysis in Three-Component Alkyl-Fluorination of Olefins with a Fluoride Ion
Weili Deng, Weiwei Feng, Yajun Li* and Hongli Bao*
*Fujian Institute of Research on the Structure of Matter,
University of Chinese Academy of Sciences, 155 Yangqiao Road West, Fuzhou,
Fujian 350002, People's Republic of China, Email: liyajun
fjirsm.ac.cn,
hlbaofjirsm.ac.cn
W. Deng, W. Feng, Y. Li, H. Bao, Org. Lett., 2018, 20, 4245-4249.
DOI: 10.1021/acs.orglett.8b01658
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Abstract
A light-induced, Ru-catalyzed three-component alkyl-fluorination of olefins under mild reaction conditions provides a wide range of fluorinated products with good functional group tolerance. A key advantage of this photoredox reaction is the use of generic alkyl groups and nucleophilic fluoride.
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Key Words
fluorination, alkylation, multicomponent reactions, photochemistry
ID: J54-Y2018
