Organic Chemistry Portal



Copper-Catalyzed Difunctionalization of Allenes with Sulfonyl Iodides Leading to (E)-α-Iodomethyl Vinylsulfones

Ning Lu, Zhiguo Zhang*, Nana Ma, Conghui Wu, Guisheng Zhang*, Qingfeng Liu and Tongxin Liu

*School of Chemistry and Chemical Engineering, Henan Normal University, Xinxiang, Henan 453007, China, Email:,

N. Lu, Z. Zhang, N. Ma, C. Wu, G. Zhang, Q. Liu, T. Liu, Org. Lett., 2018, 20, 4318-4322.

DOI: 10.1021/acs.orglett.8b01765

see article for more reactions


A highly regioselective iodosulfonylation of allenes in the presence of CuI and 1,10-phenanthroline provides useful (E)-α-iodomethyl vinylsulfones in good yields under very mild conditions. This practical reaction is fast and operationally simple.

see article for more examples

Key Words

vinyl sulfones, iodination

ID: J54-Y2018