Tandem Catalysis: Transforming Alcohols to Alkenes by Oxidative Dehydroxymethylation
Xuesong Wu, Faben A. Cruz, Alexander Lu, Vy M. Dong*
*Department of Chemistry, University of California−Irvine, Irvine, California 92697-2025, United States, Email: dongv
uci.edu
X. Wu, F. A. Cruz, A. Lu, V. M. Dong, J. Am. Chem. Soc., 2018, 140, 10126-10130.
DOI: 10.1021/jacs.8b06069
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Abstract
A Rh-catalyzed dehomologation of primary alcohols enables the synthesis of olefins via an oxidation-dehydroformylation sequence in the presence of N,N-dimethylacrylamide as hydrogen acceptor. Alcohols with diverse functionality and structure undergo oxidative dehydroxymethylation to access the corresponding olefins.
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Key Words
ID: J48-Y2018
