One-Pot Preparation of Stable Organoboronate Reagents for the Functionalization of Unsaturated Four- and Five-Membered Carbo- and Heterocycles
Andreas N. Baumann, Michael Eisold, Arif Music, Dorian Didier*
*Department of Chemistry and Pharmacy, Ludwig-Maximilians-University, Butenandtstraße 5-13, 81377 Munich, Germany, Email: dorian.didier
cup.uni-muenchen.de
A. N. Baumann, M. Eisold, A. Music, D. Didier, Synthesis, 2018, 50, 3149-3160.
DOI: 10.1055/s-0036-1592004
see article for more reactions
Abstract
The facile preparation of organoboronates and their remarkable stability and functional group tolerance enable straightforward syntheses of four- and five-membered carbo- and heterocycles via in situ transmetalation of sensitive organometallics with boron alkoxides.
see article for more examples
Methods for the Synthesis of Substituted Azetines
A. N. Baumann, M. Eisold, A. Music, G. Haas, Y. M. Kiw, D. Didier, Org. Lett., 2017, 19, 5681-5684.
Parallel Approaches for the Functionalization of Thietes: α-Metalation versus C-H Activation
M. Eisold, A. Müller-Deku, F. Reiners, D. Didier, Org. Lett., 2018, 20, 4654-4658.
Key Words
cyclobutenes, cyclopentenes, azetines, one-pot sequences
ID: J66-Y2018
