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Boron-Catalyzed O-H Bond Insertion of α-Aryl α-Diazoesters in Water

Htet Htet San, Shi-Jun Wang, Min Jiang, Xiang-Ying Tang*

*School of Chemistry and Chemical Engineering, Huazhong University of Science and Technology, 1037 Luoyu Road, Wuhan 430074, People’s Republic of China, Email: xytanghust.edu.cn

H. H. San, S.-J. Wang, M. Jiang, X.-Y. Tang, Org. Lett., 2018, 20, 4672-4676.

DOI: 10.1021/acs.orglett.8b01988 (free Supporting Information)


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Abstract

A catalytic, metal-free O-H bond insertion of α-diazoesters in water in the presence of a catalytic amount of B(C6F5)3 provides a series of α-hydroxyesters in very good yields.

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Key Words

α-hydroxyesters


ID: J54-Y2018