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Synthesis of Triarylmethanes via Palladium-Catalyzed Suzuki Coupling of Trimethylammonium Salts and Arylboronic Acids

Zhenming Zhang, Hui Wang, Nianli Qiu, Yujing Kong, Wenjuan Zeng, Yongquan Zhang, Junfeng Zhao*

*Key Laboratory of Chemical Biology of Jiangxi Province, College of Chemistry and Chemical Engineering, Jiangxi Normal University, Nanchang 330022, P.R. China, Email:

Z. Zhang, H. Wang, N. Qiu, Y. Kong, W. Zeng, Y. Zhang, J. Zhao, J. Org. Chem., 2018, 83, 8710-8715.

DOI: 10.1021/acs.joc.8b00965 (free Supporting Information)

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An efficient palladium-catalyzed Suzuki coupling of 1,1-diarylmethyl-trimethylammonium triflates with arylboronic acids provides triarylmethane derivatives in very good yields. The reaction offeres broad substrate scope and tolerates reactive functional groups such as vinyl and formyl groups.

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Key Words

arylation, Suzuki coupling

ID: J42-Y2018