Metal-free Reduction of Nitro Aromatics to Amines with B2(OH)4/H2O
Danyi Chen, Yanmei Zhou, Haifeng Zhou*, Sensheng Liu, Qixing Liu, Kaili Zhang, Yasuhiro Uozumi*
*College of Biological and Pharmaceutical Sciences, China Three Gorges University, Yichang 443002, P. R. of China; Institute for Molecular Science (IMS), Myodaiji, Okazaki 444-8787, Japan, Email: zhouhfctgu.edu.cn, uoims.ac.jp
D. Chen, Y. Zhou, H. Zhou, S. Liu, Q. Liu, K. Zhang, Y. Uozumi, Synthesis, 2018, 50, 1765-1768.
DOI: 10.1055/s-0037-1610086 (free Supporting Information)
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A metal-free reduction of nitro aromatics is mediated by tetrahydroxydiboron under mild conditions in water as solvent to provide various aromatic amines with good functional group tolerance and in good yields.
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