Photoinduced Deaminative Borylation of Alkylamines
Jingjing Wu, Lin He, Adam Noble, Varinder K. Aggarwal*
*School of Chemistry, University of Bristol, Cantock's Close,
Bristol BS8 1TS, U.K., Email: v.aggarwal
bristol.ac.uk
J. Wu, L. He, A. Noble, V. K. Aggarwal, J. Am. Chem. Soc., 2018, 140, 10700-10704.
DOI: 10.1021/jacs.8b07103
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Abstract
The formation of electron-donor-acceptor complexes between N-alkylpyridinium salts and bis(catecholato)diboron enables photoinduced single-electron transfer and fragmentation to carbon-centered radicals, which are subsequently borylated. This mild and operationally simple deaminative borylation allow a diverse range of readily available alkylamines to be efficiently converted into synthetically valuable alkylboronic esters under catalyst-free conditions.
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Key Words
alkyl boronates, photochemistry
ID: J48-Y2018
