Regioselective Access to 3-Aryl-1-aminoisoquinolines via Nickel(I)-Catalyzed C-C and C-N Cascade Coupling Reactions from the Substituted 2-(Cyanomethyl)benzonitriles
Xicheng Yang, Haihua Yu, Yulong Xu, Liming Shao*
*School of Pharmacy, Fudan University, 826 Zhangheng Road, Zhangjiang Hi-tech Park, Pudong, Shanghai 201203, China,
Email: limingshao
fudan.edu.cn
X. Yang, H. Yu, Y. Xu, L. Shao, J. Org. Chem., 2018, 83, 9682-9695.
DOI: 10.1021/acs.joc.8b01159
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Abstract
Regioselective Ni(I)-catalyzed reactions of 2-(cyanomethyl)benzonitriles with arylboronic acids provide atom-economic access to 3-aryl-1-aminoisoquinolines via C-C and C-N cascade coupling reactions.
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Key Words
ID: J42-Y2018
