Organic Chemistry Portal



Visible-Light-Enabled Construction of Thiocarbamates from Isocyanides, Thiols, and Water at Room Temperature

Wei Wei*, Pengli Bao, Huilan Yue*, Sitong Liu, Leilei Wang, Yudong Li, Daoshan Yang

*Qingdao University of Science and Technology, Qingdao 266042; Qinghai Provincial Key Laboratory of Tibetan Medicine Research, Qinghai 810008, China, P. R. China, Email:,

W. Wei, P. Bao, H. Yue, S. Liu, L. Wang, Y. Li, D. Yang, Org. Lett., 2018, 20, 5291-5295.

DOI: 10.1021/acs.orglett.8b02231

see article for more reactions


A convenient visible-light-induced reaction of isocyanides, thiols, and water under mild reaction conditions provides various thiocarbamates in good yields in the presence of cheap Rose Bengal as the photocatalyst.

see article for more examples

Key Words

thiocarbamates, air, photochemistry

ID: J54-Y2018