Iridium-Catalyzed Isomerization of N-Sulfonyl Aziridines to Allyl Amines

Albert Cabré, Giuseppe Sciortino, Gregori Ujaque, Xavier Verdaguer, Agustí Lledós*, Antoni Riera*

*Universitat Autònoma de Barcelona, Cerdanyola del Vallès, Barcelona 08193; The Barcelona Institute of Science and Technology, Baldiri Reixac 10, Barcelona 08028, Spain, Email: agustiklingon.uab.es, antoni.rierairbbarcelona.org

A. Cabré, G. Sciortino, G. Ujaque, X. Verdaguer, A. Lledós, A. Riera, Org. Lett., 2018, 20, 5747-5751.

DOI: 10.1021/acs.orglett.8b02450

---

see article for more reactions

Abstract

The Crabtree's reagent catalyzes the isomerization of N-sulfonyl 2,2-disubstituted aziridines to allyl amines under mild conditions without activation of the catalyst by hydrogen.

see article for more examples

---

---

Key Words

isomerizations, allylic amines

---

ID: J54-Y2018