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An Organodiselenide with Dual Mimic Function of Sulfhydryl Oxidases and Glutathione Peroxidases: Aerial Oxidation of Organothiols to Organodisulfides

Vandana Rathore, Aditya Upadhyay, Sangit Kumar*

*Department of Chemistry, Indian Institute of Science Education and Research (IISER) Bhopal, Bhopal By-pass Road, Bhauri, Bhopal 462 066, Madhya Pradesh India, Email:

V. Rathore, A. Upadhyay, S. Kumar, Org. Lett., 2018, 20, 6274-6278.

DOI: 10.1021/acs.orglett.8b02756


An organodiselenide catalyzed the aerobic oxidation of thiols into disulfides in practical yields without any reagents/additives, base, and light source. The synthesized diselenide also catalyzes the reduction of hydrogen peroxide into water.

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Key Words

disulfides, oxygen

ID: J54-Y2018