Light-Driven Intermolecular Charge Transfer Induced Reactivity of Ethynylbenziodoxol(on)e and Phenols
Bin Liu, Chern-Hooi Lim, Garret M. Miyake*
*Department of Chemistry, Colorado State University, Fort Collins, Colorado 80523, United States, Email: garret.miyakecolostate.edu
B. Liu, C.-H. Lim, G. M. Miyake, J. Am. Chem. Soc., 2018, 140, 12829-12835.
DOI: 10.1021/jacs.8b05870 (free Supporting Information)
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The reaction between ethynylbenziodoxol(on)es (EBXs) and phenols driven by visible light provides (Z)-2-iodovinyl phenyl ethers with excellent regio- and stereoselectivity. The (Z)-2-iodovinyl phenyl ether products can be further stereospecifically functionalized to form trisubstituted alkenes, demonstrating the potential of these products en route to chemical complexity.
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