Organic Chemistry Portal

Abstracts

Search:

Rhodium-Catalyzed Generation of Anhydrous Hydrogen Iodide: An Effective Method for the Preparation of Iodoalkanes

Chaoyuan Zeng, Guoli Shen, Fan Yang, Jingchao Chen*, Xuexin Zhang, Cuiping Gu, Yongyun Zhou, Baomin Fan*

*YMU-HKBU Joint Laboratory of Traditional Natural Medicine, Yunnan Minzu University, Kunming 650500, China, Email: chenjingchao84163.com, adams.bmfhotmail.com

C. Zeng, G. Shen, F. Yang, J. Chen, X. Zhang, C. Gu, Y. Zhou, B. Fan, Org. Lett., 2018, 20, 6859-6862.

DOI: 10.1021/acs.orglett.8b02980


see article for more reactions

Abstract

Anhydrous hydrogen iodide preparated directly from molecular hydrogen and iodine using a rhodium catalyst is highly active in the transformations of alkenes, phenyl aldehydes, alcohols, and cyclic ethers to the corresponding iodoalkanes. Therefore, the present methodology offers a practical method for the preparation of various iodoalkanes in excellent atom economy.

see article for more examples



Key Words

benzyl iodides, alkyl iodides, hydrogen


ID: J54-Y2018