Base-Controlled Three Component Reactions of Amines, Elemental Sulfur, and Styrenes: Synthesis of Thioamides under Metal-Free Conditions
Pingshun Zhang, Wanzhi Chen*, Miaochang Liu, Huayue Wu*
*Department of Chemistry, Zhejiang University, Yuquan Campus, Hangzhou 310007; College of Chemistry and Materials Engineering, Wenzhou University, Wenzhou 325027, China, Email: chenwzzzju.edu.cn, hywu3163.com
P. Zhang, W. Chen, M. Liu, H. Wu, J. Org. Chem., 2018, 83, 14269-14276.
DOI: 10.1021/acs.joc.8b01721 (free Supporting Information)
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Base-controlled three component reactions of styrenes, amines, and sulfur provide thioamides. Depending on the base, 2-phenylethanethioamides and benzothioamides were obtained selectively.
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