Palladium-Catalyzed Reductive Coupling of Nitroarenes with Phenols leading to N-Cyclohexylanilines
Kai-Jian Liu, Xiu-Ling Zeng, Yong Zhang, Yi Wang, Xin-Sheng Xiao, Huilan Yue, Ming Wang, Zilong Tang, Wei-Min He*
*Hunan Provincial Engineering Research Center for Ginkgo
biloba, Hunan University of Science and Engineering, Yongzhou 425100, P. R. of China,
Email: weiminhe2016
yeah.net
K.-J. Liu, X.-L. Zeng, Y. Zhang, Y. Wang, X.-S. Xiao, H. Yue, M. Wang, Z. Tang, W.-M. He, Synthesis, 2018, 50, 4637-4644.
DOI: 10.1055/s-0037-1610231
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Abstract
A direct and efficient palladium-catalyzed reductive coupling of nitroarenes with phenols provides various N-cyclohexylaniline derivatives in good yields using safe and inexpensive sodium formate as the hydrogen donor.
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Key Words
green chemistry, palladium catalysis, reductive coupling, sodium formate, nitroarenes, phenol, cyclohexylamines, amines
ID: J66-Y2018
