Visible-Light-Promoted C-S Cross-Coupling via Intermolecular Charge Transfer
Bin Liu, Chern-Hooi Lim, Garret M. Miyake*
*Department of Chemistry, Colorado State University, Fort Collins, Colorado 80523, United States, Email: garret.miyakecolostate.edu
B. Liu, C. H. Lim, G. M. Miyake, J. Am. Chem. Soc., 2017, 139, 13616-13619.
DOI: 10.1021/jacs.7b07390 (free Supporting Information)
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A mild, scalable, visible-light-promoted cross-coupling reaction between thiols and aryl halides provides various aryl thioethers in the absence of both transition metal and photoredox catalysts. This C-S coupling protocol was also applied in late-stage modifications of active pharmaceutical ingredients.
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diaryl sulfides, photochemistry