Nickel-Catalyzed Cross-Electrophile Coupling between Benzyl Alcohols and Aryl Halides Assisted by Titanium Co-reductant
Takuya Suga*, Yutaka Ukaji*
*Division of Material Chemistry, Graduate School of Natural Science and Technology, Kanazawa University, Kakuma, Kanazawa, Ishikawa 920-1192, Japan, Email: suga-tse.kanazawa-u.ac.jp, ukajistaff.kanazawa-u.ac.jp
T. Suga, Y. Ukaji, Org. Lett., 2018, 20, 7846-7850.
DOI: 10.1021/acs.orglett.8b03367 (free Supporting Information)
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A nickel-catalyzed cross-electrophile coupling reaction between benzyl alcohols and aryl halides is mediated by a low-valent titanium reagent generated from TiCl4(2,6-lutidine) and manganese powder. The reaction afforded the cross-coupled product in high yield.
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