Organic Chemistry Portal

Abstracts

Search:

Microwave-Assisted Nickel-Catalyzed Synthesis of Benzimidazoles: Ammonia as a Cheap and Nontoxic Nitrogen Source

Fang Ke*, Peng Zhang, Yiwen Xu, Xiaoyan Lin, Jin Lin, Chen Lin, Jianhua Xu

*College of Pharmacy, Fujian Medical University, Fuzhou 350004, P. R. of China, Email: kefangmail.fjmu.edu.cn

F. Ke, P. Zhang, Y. Xu, X. Lin, J. Lin, C. Lin, J. Xu, Synlett, 2018, 29, 2722-2726.

DOI: 10.1055/s-0037-1610843


see article for more reactions

Abstract

An efficient and convenient Ni-catalyzed C-N bond formation enables the synthesis of various benzimidazoles in excellent yields from various 2-haloanilines, aldehydes, and ammonia as nitrogen source.

see article for more examples



Key Words

nickel catalysis, C-N bond formation, benzimidazoles, microwave synthesis, ammonia


ID: J72-Y2018