Microwave-Assisted Nickel-Catalyzed Synthesis of Benzimidazoles: Ammonia as a Cheap and Nontoxic Nitrogen Source
Fang Ke*, Peng Zhang, Yiwen Xu, Xiaoyan Lin, Jin Lin, Chen Lin, Jianhua Xu
*College of Pharmacy, Fujian Medical University, Fuzhou 350004, P. R. of China, Email: kefangmail.fjmu.edu.cn
F. Ke, P. Zhang, Y. Xu, X. Lin, J. Lin, C. Lin, J. Xu, Synlett, 2018, 29, 2722-2726.
DOI: 10.1055/s-0037-1610843 (free Supporting Information)
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An efficient and convenient Ni-catalyzed C-N bond formation enables the synthesis of various benzimidazoles in excellent yields from various 2-haloanilines, aldehydes, and ammonia as nitrogen source.
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