Organic Chemistry Portal



Electrochemical Dehydrogenative Phosphorylation of Alcohols for the Synthesis of Organophosphinates

Lingling Deng, Yang Wang, Haibo Mei, Yi Pan, Jianlin Han*

*Jiangsu Key Laboratory of Advanced Organic Materials, Nanjing University, Nanjing 210093, China, Email:

L. Deng, Y. Wang, H. Mei, Y. Pan, J. Han, J. Org. Chem., 2019, 84, 949-956.

DOI: 10.1021/acs.joc.8b02882

see article for more reactions


An electrochemical cross-dehydrogenative-coupling reaction between alcohols and secondary phosphine oxides provides organophosphinates in an eco-friendly and efficient manner at room temperature without the addition of any oxidant, metal catalyst, or additive.

see article for more examples

proposed mechanism

Key Words

organophosphinates, electrochemistry

ID: J42-Y2019