Cationic Iridium Complex-Catalyzed Intermolecular Hydroalkylation of Unactivated Alkenes with 1,3-Diketones
Ryo Takeuchi*, Jun Sagawa, Masaki Fujii, Masaki Fujii
*Department of Chemistry and Biological Science, Aoyama Gakuin University, 5-10-1 Fuchinobe, Chuo-ku, Sagamihara, Kanagawa 252-5258, Japan,
Email: takeuchi
chem.aoyama.ac.jp
R. Takeuchi, J. Sagawa, M. Fujii, M. Fujii, J. Waser, Org. Lett., 2019, 21, 741-744.
DOI: 10.1021/acs.orglett.8b03975
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Abstract
A cationic iridium catalyst enables an intermolecular hydroalkylation of 1,3-diketones with unactivated terminal alkenes under neutral conditions to provide Markovnikov products in good yield.
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Key Words
ID: J54-Y2019
