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Multifunctionalization of Unactivated Cyclic Ketones via an Electrochemical Process: Access to Cyclic α-Enaminones

Kangfei Hu, Peng Qian, Ji-Hu Su, Zhibin Li, Jiawei Wang, Zhenggen Zha*, Zhiyong Wang*

*School of Chemistry and Material Science, University of Science and Technology of China, Hefei, Anhui 230026, P. R. China, Email:,

K. Hu, P. Qian, J.-H. Su, Z. Li, J. Wang, Z. Zha, Z. Wang, J. Org. Chem., 2019, 84, 1647-1653.

DOI: 10.1021/acs.joc.8b02930

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An electrochemically intermolecular α-amination of cyclopentanone with a broad range of anilines provides various α-enaminones under metal-free conditions in very good yields in one step.

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Key Words

cyclopentenones, α-ketoenamines, electrochemistry

ID: J42-Y2019