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Alkenyl Exchange of Allylamines via Nickel(0)-Catalyzed C-C Bond Cleavage

Chao Fan, Xin-Yang Lv, Li-Jun Xiao*, Jian-Hua Xie, Qi-Lin Zhou*

*College of Chemistry, Nankai University, Tianjin 300071, China, Email: 1120140207mail.nankai.edu.cn, qlzhounankai.edu.cn

C. Fan, X.-Y. Lv, L.-J. Xiao, J.-H. Xie, Q.-L. Zhou, J. Am. Chem. Soc., 2019, 141, 2889-2893.

DOI: 10.1021/jacs.8b13251 (free Supporting Information)



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Abstract

Nickel-catalyzed C-C bond cleavage and formation enables a functional group exchange reaction between allylamines and alkenes to provide allylamines, which are widely used in the production of pharmaceuticals, agrochemicals, and fine chemicals.

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proposed mechanism



Key Words

allylic amines


ID: J48-Y2019