Palladium-Catalyzed Methylation of Aryl, Heteroaryl, and Vinyl Boronate Esters
Alexander M. Haydl, John F. Hartwig*
*Department of Chemistry, University of California, Berkeley, California 94720, United States,
Email: jhartwig
berkeley.edu
A. M. Haydl, J. F. Hartwig, Org. Lett., 2019, 21, 1337-1341.
DOI: 10.1021/acs.orglett.9b00025
Abstract
A Pd-catalyzed direct methylation of aryl, heteroaryl, and vinyl boronate esters with iodomethane occurs with a remarkably broad scope and is suitable for late-stage derivatization of biologically active compounds.
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Key Words
ID: J54-Y2019
