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Dehydrogenative Synthesis of Quinolines, 2-Aminoquinolines, and Quinazolines Using Singlet Diradical Ni(II)-Catalysts

Gargi Chakraborty, Rina Sikari, Siuli Das, Rakesh Mondal, Suman Sinha, Seemika Banerjee, Nanda D. Paul*

*Department of Chemistry, Indian Institute of Engineering Science and Technology, Shibpur, Botanic Garden, Howrah 711103, India, Email:

G. Chakraborty, R. Sikari, S. Das, R. Mondal, S. Sinha, S. Banerjee, N. D. Paul, J. Org. Chem., 2019, 84, 2626-2641.

DOI: 10.1021/acs.joc.8b03070

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Singlet diradical Ni(II) featuring two antiferromagnetically coupled singlet diradical diamine type ligands catalyzes simple, straightforward, and atom economic syntheses of quinolines, 2-aminoquinolines, and quinazolines in good yields via biomimetic dehydrogenative condensation/coupling reactions.

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Key Words

quinolines, quinazolines, oxygen

ID: J42-Y2019