Dinuclear Zinc-AzePhenol Catalyzed Asymmetric Aza-Henry Reaction of N-Boc Imines and Nitroalkanes under Ambient Conditions
Shanshan Liu, Wen-Chao Gao, Yu-Hang Miao, Min-Can Wang*
*The College of Chemistry and Molecular Engineering, Zhengzhou University, No. 75 Daxue Road, Zhengzhou, Henan 450052, P. R. China, Email: wangmincanzzu.edu.cn
S. Liu, W.-C. Gao, Y.-H. Miao, M.-C. Wang, J. Org. Chem., 2019, 84, 2654-2659.
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A dinuclear zinc-AzePhenol complex catalyzes an asymmetric aza-Henry reaction of N-Boc imines and nitroalkanes to provide various nitroamines in good yields with excellent enantioselectivities and high diasteroselectivity. The method offers operational simplicity and mild reaction conditions.
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Henry reaction, nitro compounds