Perhydrolysis in Ethereal H2O2 Mediated by MoO2(acac)2: Distinct Chemoselectivity between Ketones, Ketals, and Epoxides
Xiaosheng An, Qinghong Zha, Yikang Wu*
*State Key Laboratory of Bioorganic and Natural Products Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 345 Lingling Road, Shanghai 200032, China, Email: yikangwumail.sioc.ac.cn
X. An, Q. Zha, Y. Wu, Org. Lett., 2019, 21, 1542-1546.
DOI: 10.1021/acs.orglett.9b00425 (free Supporting Information)
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Ketones, ketals, and epoxides can be converted to the corresponding hydroperoxides in high yields and with high chemoselectivity by reaction with ethereal H2O2 in the presence of a catalytic amount of MoO2(acac)2.
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Y. Li, H.-D. Hao, Q. Zhang, Y. Wu, Org. Lett., 2009, 11, 1615-1618.