N-Pyridinyl Sulfilimines as a Source for α-Imino Gold Carbenes: Access to 2-Amino-Substituted N-Fused Imidazoles
Xianhai Tian, Lina Song, Matthias Rudolph, Qian Wang, Xinlong Song, Frank Rominger, A. Stephen K. Hashmi*
*Institut für Organische Chemie, Universität Heidelberg, Im Neuenheimer Feld 270, Heidelberg 69120, Germany, Email: hashmihashmi.de
X. Tian, L. Song, M. Rudolph, Q. Wang, X. Song, F. Rominger, A. S. K. Hashmi, Org. Lett., 2019, 21, 1558-1601.
DOI: 10.1021/acs.orglett.9b00140
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Abstract
Gold-catalyzed formal 1,3-dipolar annulation between readily accessible N-pyridinylsulfilimines and ynamides provides a diverse set of imidazole derivatives. These functionalized cyclic products can undergo further transformations to afford diverse imidazole frameworks.
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Key Words
ID: J54-Y2019