Organic Chemistry Portal

Abstracts

Search:

Metal-Free Synthesis of 2-Arylbenzothiazoles from Aldehydes, Amines, and Thiocyanate

Amrita Dey, Alakananda Hajra*

*Department of Chemistry, Visva-Bharati (A Central University), Santiniketan 731235, India, Email: alakananda.hajravisva-bharati.ac.in

A. Dey, A. Hajra, Org. Lett., 2019, 21, 1686-1689.

DOI: 10.1021/acs.orglett.9b00245 (free Supporting Information)



see article for more reactions

Abstract

A highly efficient reaction of readily available aromatic amines, benzaldehydes, and NH4SCN as a sulfur source provides 2-arylbenzothiazoles with wide functional group compatibility in good yields via an iodine-mediated oxidative annulation.


see article for more examples



Key Words

benzothiazoles, iodine, multicomponent reactions


ID: J54-Y2019