Visible-Light-Initiated Manganese-Catalyzed E-Selective Hydrosilylation and Hydrogermylation of Alkynes

Hao Liang, Yun-Xing Ji, Rui-Han Wang, Zhi-Hao Zhang*, Bo Zhang*

*State Key Laboratory of Natural Medicines, China Pharmaceutical University, 24 Tongjia Xiang, Nanjing 210009, China, Email: 1620174425cpu.edu.cn, zb3981444cpu.edu.cn

H. Liang, Y.-X. Ji, R.-H. Wang, Z.-H. Zhang, B. Zhang, Org. Lett., 2019, 21, 2750-2754.

DOI: 10.1021/acs.orglett.9b00701

---

see article for more reactions

Abstract

Manganese-photocatalyzed activation of the Si-H bond in silanes enables a mild and efficient hydrosilylation of alkynes with high regioselectivity (anti-Markovnikov) and stereoselectivity to provide a wide range of Z-vinylsilanes in high yields. Moreover, visible-light-induced manganese-catalyzed activation of the Ge-H bond enables an E-selective alkyne hydrogermylation.

see article for more examples

---

---

Key Words

vinylsilanes, photochemistry

---

ID: J54-Y2019