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Sustainable Synthesis of Quinazoline and 2-Aminoquinoline via Dehydrogenative Coupling of 2-Aminobenzyl Alcohol and Nitrile Catalyzed by Phosphine-Free Manganese Pincer Complex

Kalicharan Das, Avijit Mondal, Debjyoti Pal, Dipankar Srimani*

*Department of Chemistry, Indian Institute of Technology-Guwahati, Kamrup, Assam 781039, India, Email:

K. Das, A. Mondal, D. Pal, D. Srimani, Org. Lett., 2019, 21, 3223-3227.

DOI: 10.1021/acs.orglett.9b00939

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A sustainable synthesis of quinazoline and 2-aminoquinoline via acceptorless dehydrogenative annulation is catalyzed by earth-abundant well-defined manganese complexes bearing NNS ligands.

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ID: J54-Y2019