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Copper-Catalyzed N-Arylation of Sulfoximines with Arylboronic Acids under Mild Conditions

Surabhi Gupta, Siddharth Baranwal, Nalluchamy Muniyappan, Shahulhameed Sabiah, Jeyakumar Kandasamy*

*Department of Chemistry, Indian Institute of Technology (BHU), 221005 Varanasi, Uttar Pradesh, India, Email:

S. Gupta, S. Baranwal, N. Muniyappan, S. Sabiah, J. Kandasamy, Synthesis, 2019, 51, 2171-2182.

DOI: 10.1055/s-0037-1612216

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The use of copper(I) iodide and 4-DMAP achieves a N-arylation of sulfoximines with various arylboronic acids, including sterically substrates, in excellent yields at room temperature within a short span of time.

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Key Words

arylation, Chan-Lam coupling, boronic acids, sulfoximines, catalysis, copper

ID: J66-Y2019