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Enones from Acid Fluorides and Vinyl Triflates by Reductive Nickel Catalysis

Feng-Feng Pan, Peng Guo, Chun-Ling Li, Peifeng Su, Xing-Zhong Shu*

*State Key Laboratory of Applied Organic Chemistry, College of Chemistry and Chemical Engineering, Lanzhou University, 222 South Tianshui Road, Lanzhou, 730000, China, Email: shuxingzhlzu.edu.cn

F.-F. Pan, P. Guo, C.-L. Li, P. Su, X.-Z. Shu, Org. Lett., 2019, 21, 3701-3705.

DOI: 10.1021/acs.orglett.9b01164 (free Supporting Information)



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Abstract

A nickel-catalyzed reductive coupling between vinyl triflates and acid fluorides provides an efficient access to various enones. The reaction avoids the use of acyl or vinyl metallic reagents, proceeds with a broad range of acid fluorides and cyclic vinyl triflates, and tolerates several functional groups.

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Key Words

enones, cyclohexenes, manganese


ID: J54-Y2019