Enones from Acid Fluorides and Vinyl Triflates by Reductive Nickel Catalysis
Feng-Feng Pan, Peng Guo, Chun-Ling Li, Peifeng Su, Xing-Zhong Shu*
*State Key Laboratory of Applied Organic Chemistry, College of Chemistry and Chemical Engineering, Lanzhou University, 222 South Tianshui Road, Lanzhou, 730000, China,
Email: shuxingzh
lzu.edu.cn
F.-F. Pan, P. Guo, C.-L. Li, P. Su, X.-Z. Shu, Org. Lett., 2019, 21, 3701-3705.
DOI: 10.1021/acs.orglett.9b01164
see article for more reactions
Abstract
A nickel-catalyzed reductive coupling between vinyl triflates and acid fluorides provides an efficient access to various enones. The reaction avoids the use of acyl or vinyl metallic reagents, proceeds with a broad range of acid fluorides and cyclic vinyl triflates, and tolerates several functional groups.
see article for more examples
Key Words
enones, cyclohexenes, manganese
ID: J54-Y2019
