Enones from Acid Fluorides and Vinyl Triflates by Reductive Nickel Catalysis
Feng-Feng Pan, Peng Guo, Chun-Ling Li, Peifeng Su, Xing-Zhong Shu*
*State Key Laboratory of Applied Organic Chemistry, College of Chemistry and Chemical Engineering, Lanzhou University, 222 South Tianshui Road, Lanzhou, 730000, China, Email: shuxingzhlzu.edu.cn
F.-F. Pan, P. Guo, C.-L. Li, P. Su, X.-Z. Shu, Org. Lett., 2019, 21, 3701-3705.
DOI: 10.1021/acs.orglett.9b01164 (free Supporting Information)
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A nickel-catalyzed reductive coupling between vinyl triflates and acid fluorides provides an efficient access to various enones. The reaction avoids the use of acyl or vinyl metallic reagents, proceeds with a broad range of acid fluorides and cyclic vinyl triflates, and tolerates several functional groups.
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