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Trichloroisocyanuric Acid Mediated High-Yielding Synthesis of N-Acylbenzotriazoles under Mild Reaction Conditions

Mala Singh, Anoop S. Singh, Nidhi Mishra, Anand K. Agrahari, Vinod K. Tiwari*

*Department of Chemistry, Institute of Science, Banaras Hindu University, Varanasi, 221005, India, Email:

M. Singh, A. S. Singh, N. Mishra, A. K. Agrahari, V. K. Tiwari, Synthesis, 2019, 51, 2183-2190.

DOI: 10.1055/s-0037-1611724 (free Supporting Information)


A convenient reaction of carboxylic acids with 1H-benzotriazole provides N-acylbenzotriazoles in good yields in the presence of only 0.35 equivalent of trichloroisocyanuric acid and 1.2 equivalents of PPh3.

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An Improved N-Acylation of 1H-Benzotriazole Using 2,2′-Dipyridyl­di­sulfide and Triphenylphosphine

A. S. Singh, A. K. Agrahari, N. Mishra, M. Singh, V. K. Tiwari, Synthesis, 2019, 51, 470-476.

Key Words

N-acylbenzotriazoles, benzotriazoles, coupling reactions, acylation

ID: J66-Y2019