Palladium-Catalyzed C-P Cross-Coupling between (Het)aryl Halides and Secondary Phosphine Oxides
Gladis G. Zakirova, Dmitrii Yu. Mladentsev, Nataliya E. Borisova*
*Department of Chemistry, Lomonosov Moscow State University, 1/3 Leninskie Gory, GSP-1, 119991 Moscow, Russian Federation,
Email: borisova.nataliya
gmail.com
G. G. Zajkirova, D: Y. Mladentsev, N. E. Borisova, Synthesis, 2019, 51, 2379-2386.
DOI: 10.1055/s-0037-1610698
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Abstract
A palladium-catalyzed C-P bond formation between dichloroheterocycles and secondary phosphine oxides provides heterocyclic compounds bearing two tertiary phosphine oxides in good yields. Extension of the methodology to monohalohetarenes and monohaloarenes was successfully carried out; the steric and electronic properties of the halides were varied widely.
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Key Words
cross-coupling, palladium, phosphine oxides, heterocycles, homogeneous catalysis
ID: J66-Y2019
