Ru^II-Catalyzed/NH₂-Assisted Selective Alkenyl C-H [5 + 1] Annulation of Alkenylanilines with Sulfoxonium Ylides to Quinolines

Pu Chen, Jiang Nan*, Yan Hu, Qiong Ma, Yangmin Ma*

*Shaanxi Key Laboratory of Chemical Additives for Industry, College of Chemistry and Chemical Engineering, Shaanxi University of Science and Technology, Xi’an 710021, China, Email: mym63sina.com

P. Chen, J. Nan, Y. Hu, Q. Ma, Y. Ma, Org. Lett., 2019, 21, 4812-4815.

DOI: 10.1021/acs.orglett.9b01702

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Abstract

A ruthenium-catalyzed [5 + 1] annulation of 2-alkenylanilines with sulfoxonium ylides provides highly functionalized quinolines with good yields and excellent functional group tolerance.

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Key Words

quinolines, oxygen

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ID: J54-Y2019