Chiral Bidentate Boryl Ligand Enabled Iridium-Catalyzed Enantioselective C(sp3)-H Borylation of Cyclopropanes
Yongjia Shi, Qian Gao, Senmiao Xu*
*Suzhou Research Institute, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou 730000, China, Email: senmiaoxulicp.cas.cn
Y. Shi, Q. Gao, S. Xu, J. Am. Chem. Soc., 2019, 141, 10599-10604.
DOI: 10.1021/jacs.9b04549 (free Supporting Information)
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An Ir-catalyzed enantioselective C(sp3)-H borylation of cyclopropanecarboxamides using a chiral bidentate boryl ligand provides β-borylated products with good to excellent enantioselectivities. The borylated products can be used as versatile precursors.
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