Ruthenium-Catalyzed Synthesis of N-Methylated Amides using Methanol
Bhaskar Paul, Dibyajyoti Panja, Sabuj Kundu*
*Department of Chemistry, Indian Institute of Technology, Kanpur, Uttar Pradesh 208016, India,
Email: sabuj
iitk.ac.in
B. Paul, D. Panja, S. Kundu, Org. Lett., 2019, 21, 5843-5847.
DOI: 10.1021/acs.orglett.9b01925
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Abstract
The use of a ruthenium(II) catalyst enables an efficient synthesis of N-methylated amides in the presence of methanol. In addition, a tandem C-methylation and N-methylation provided α-methyl N-methylated amides.
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Key Words
ID: J54-Y2019
