Pd-Catalyzed Carbonylation of Acyl Azides

Zongyang Li, Shiyang Xu, Baoliang Huang, Chenhui Yuan, Wenxu Chang, Bin Fu, Lei Jiao*, Peng Wang, Zhenhua Zhang*

*Department of Applied Chemistry, China Agricultural University, Beijing 100193; Department of Chemistry, Tsinghua University, Beijing 10084, China, Email: hangzhhcau.edu.cn, leijiaomail.tsinghua.edu.cn

Z. Li, S. Xu, B. Huang, C. Yuan, W. Chang, B. Fu, L. Jiao, P. Wang, Z. Zhang, J. Org. Chem., 2019, 84, 9497-9508.

DOI: 10.1021/acs.joc.9b01048

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Abstract

A simple Pd-catalyzed carbonylation reaction of acyl azides provides facile access to acyl ureas with broad substrate scope, high efficiency, and simple operation under mild conditions.

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Key Words

urea derivatives, multicomponent reactions

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ID: J42-Y2019