Pd-Catalyzed Highly Chemo- and Regioselective Hydrocarboxylation of Terminal Alkyl Olefins with Formic Acid
Wenlong Ren, Jianxiao Chu, Fei Sun, Yian Shi*
*Department of Chemistry, Colorado State University, Fort Collins, Colorado 80523, United States,
Email: yian.shi
colostate.edu
W. Ren, J. Chu, F. Sun, Y. Shi, Org. Lett., 2019, 21, 5967-5970.
DOI: 10.1021/acs.orglett.9b02101
Abstract
An efficient Pd-catalyzed hydrocarboxylation of alkenes with HCOOH provides a broad range of linear carboxylic acids bearing various functional groups with excellent chemo- and regioselectivities under mild reaction conditions. The reaction process is operationally simple and requires no handling of toxic CO.
see article for more examples
W. Liu, W. Ren, J. Li, Y. Shi, W. Chang, Y. Shi, Org. Lett., 2017, 19, 1748-1751.
An Effective Pd-Catalyzed Regioselective Hydroformylation of Olefins with Formic Acid
W. Ren, W. Chang, J. Dai, Y. Shi, J. Li, Y. Shi, J. Am. Chem. Soc., 2016, 138, 14864-14867.
Key Words
ID: J54-Y2019
