Organic Chemistry Portal



Direct Synthesis of 1-Arylprop-1-ynes with Calcium Carbide as an Acetylene Source

Lei Gao, Zheng Li*

*College of Chemistry and Chemical Engineering, Northwest Normal University, Lanzhou, Gansu 730070, P. R. of China, Email:

L. Gao, Z. Li, Synlett, 2019, 30, 1580-1584.

DOI: 10.1055/s-0037-1610718


Aromatic aldehyde p-tosylhydrazones can directly be converted into 1-arylprop-1-ynes in the presence of calcium carbide as an acetylene source. This simple protocol offers use of a readily available source of acetylene, operational simplicity, high yield, and broad substrate scope.

see article for more examples

Key Words

arylpropynes, calcium carbide, tosylhydrazones, alkynes, arylalkynes

ID: J72-Y2019