TEMPO-Me: An Electrochemically Activated Methylating Agent
Philip L. Norcott, Chelsey L. Hammill, Benjamin B. Noble, Johnathon C. Robertson, Angus Olding, Alex C. Bissember*, Michelle L. Coote*
*University of Tasmania, Hobart, Tasmania 7001; Australian National University, Canberra, Australian Capital Territory 2601, Australia
Email: alex.bissemberutas.edu.au, michelle.coote
anu.edu.au
P. L. Norcott, C. L. Hammill, B. B. Noble, J. C. Robertson, A. Olding, A. C. Bissembler, M. L. Coote, J. Am. Chem. Soc., 2019, 141, 15450-15455.
DOI: 10.1021/jacs.9b08634
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Abstract
The one-electron electrochemical oxidation of TEMPO-Me produces a powerful electrophilic methylating agent, that can be used for a methylation of aromatic acids.
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Key Words
alkylation, electrochemistry
ID: J48-Y2019