Selective Ketone Formations via Cobalt-Catalyzed β-Alkylation of Secondary Alcohols with Primary Alcohols
Bedraj Pandey, Shi Xu and Keying Ding*
*Department of Chemistry, Middle Tennessee State University, Murfreesboro, Tennessee 37132, United States,
Email: keying.ding
mtsu.edu
B. Pandey, S. Xu, K. Ding, Org. Lett., 2019, 21, 7400-7404.
DOI: 10.1021/acs.orglett.9b02727
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Abstract
An environmentally benign and atom economical cobalt-catalyzed β-alkylation of secondary alcohols with primary alcohols provides ketones via acceptorless dehydrogenative coupling. The reaction produces water and hydrogen gas as the only byproducts.
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Key Words
ID: J54-Y2019
