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Palladium-Catalyzed Cascade Annulation/Allylation of Alkynyl Oxime Ethers with Allyl Halides: Rapid Access to Fully Substituted Isoxazoles

Can Li, Jianxiao Li, Fei Zhou, Chaosheng Li and Wanqing Wu*

*School of Chemistry and Chemical Engineering, South China University of Technology, Guangzhou 510640, China, Email: cewuwqscut.edu.cn

C. Li, J. Li, F. Zhou, C. Li, W. Wu, J. Org. Chem., 2019, 84, 11958-11970.

DOI: 10.1021/acs.joc.9b01593 (free Supporting Information)


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Abstract

A mild, palladium-catalyzed cascade annulation/allylation of alkynyl oxime ethers with allyl halides provides functionalized isoxazoles with good functional group compatibility and convenient operation.

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Key Words

Isoxazoles


ID: J42-Y2019