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Synthesis of Benzylic Alcohols by C-H Oxidation

Lalita Tanwar, Jonas Börgel and Tobias Ritter*

*Max-Planck-Institut für Kohlenforschung, Kaiser-Wilhelm-Platz 1, D-45470 Mülheim an der Ruhr, Germany, Email:

L. Tanwar, J. Börgel, T. Ritter, J. Am. Chem. Soc., 2019, 141, 17983-17988.

DOI: 10.1021/jacs.9b09496

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The use of bis(methanesulfonyl) peroxide as an oxidant enables a selective synthesis of benzylic alcohols without further oxidation of alcohols to ketones. A proton-coupled electron transfer mechanism (PCET) may account for the difference in reactivity.

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Key Words

hydroxylation, bis(methanesulfonyl) peroxide

ID: J48-Y2019