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Iridium-Catalyzed B-H Bond Insertion Reactions Using Sulfoxonium Ylides as Carbene Precursors toward α-Boryl Carbonyls

Jianglian Li, Hua He, Mengyi Huang, Yuncan Chen, Yi Luo, Kaichuan Yan, Qiantao Wang* and Yong Wu*

*West China School of Pharmacy, Sichuan University, Chengdu 610041, P. R. China, Email: qiantao_wanghotmail.com, wyongscu.edu.cn

J. Li, H. He, M. Huang, Y. Chen, Y. Luo, K. Yan, Q. Wang, Org. Lett., 2019, 21, 9005-9008.

DOI: 10.1021/acs.orglett.9b03410 (free Supporting Information)


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Abstract

An iridium-catalyzed B-H bond insertion reaction between borane adducts and sulfoxonium ylides as readily available and safe substrates provides α-boryl carbonyls. Sulfonium salts and sulfonium ylides could also be amenable to the reaction.

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Key Words

boranes


ID: J54-Y2019