Pd(OAc)2-Catalyzed Asymmetric Hydrogenation of α-Iminoesters
Jianzhong Chen, Feilong Li, Fang Wang, Yawen Hu, Zhenfeng Zhang, Min Zhao* and Wanbin Zhang*
*Shanghai Jiao Tong University, 800 Dongchuan Road, Shanghai 200240; East China University of Science and Technology, Shanghai 200237, P.R. China, Email: zhaomin6502sina.com, wanbinsjtu.edu.cn
J. Chen, F. Li, F. Wang, Y. Hu, Z. Zhang, M. Zhao, W. Zhang, Org. Lett., 2019, 21, 9060-9065.
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An efficient Pd(OAc)2-catalyzed asymmetric hydrogenation of α-iminoesters at 1 atm hydrogen pressure and room temperature provides chiral α-arylglycine fragments, which are widely found in many chiral products and bioactive molecules.
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