Ni-Catalyzed Regioselective Hydroalkoxylation of Branched 1,3-Dienes
Gaël Tran and Clément Mazet*
*Department of Organic Chemistry, University of Geneva, 30
quai Ernest Ansermet, 1211 Geneva, Switzerland, Email: clement.mazet
unige.ch
G. Tran, C. Mazet, Org. Lett., 2019, 21, 9060-9065.
DOI: 10.1021/acs.orglett.9b03511
see article for more reactions
Abstract
The use of a (P,N) ligand enables a highly regioselective Ni-catalyzed hydroalkoxylation of 1,3-dienes. The optimized protocol operates under particularly mild conditions, provides access to a broad range of structurally diverse allylic ethers, and tolerates a number of sensitive functional groups.
see article for more examples
Key Words
ID: J54-Y2019
